filial generation (F1, F2): Pertaining to a particular generation in a sequence of matings. In the generation of inbred strains, the first filial generation, symbolized as F1, refers to the offspring of a cross between strains having non-identical genomes. When F1 siblings are crossed to each other, their offspring are considered to be members of the second filial generation or F2, with subsequent generations of brother-sister matings numbered with integer increments.
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